About Ketamine

Ketamine is a rapid acting antidepressant. 

Depending upon the route of administration and dosing, it can be used as a psycholytic medication for psychotherapy, or to provide a transformational experience at higher doses: 

all while providing an enhanced sense of well-being and peace.


For a Firefighter Struggling With Trauma, Ketamine Offers Hope (New York Times)

Cracking the Ketamine Code (NIMH)

I Went To A Ketamine Therapy Training. What Happened There Changed My Life. (HuffPost)

Ketamine for Depression: What it feels like and who it can help (Washington Post)

Depression: The Case for Ketamine (Mental Health Matters Podcast, Youtube) 

Relative effectiveness of antidepressant treatments in treatment-resistant depression (Nature)

Intramuscular Ketamine to Treat Major Depressive Disorder: A Case Series of Forty Patients (Sci Forschen)

Therapeutic Potential of Intravenous Ketamine in Early-Onset Dementia: A Case Report (Cureus)

A meta-analysis of the effects of ketamine on suicidal ideation in depression patients (Translational Psychiatry)

What to know about ketamine for psychiatric use (Psychology Today)

The Brain on Ketamine (Harvard Gazette)

Ketamine for the treatment of mental health and substance use disorders: comprehensive systematic review  (BJPsych Open)

Neurocognitive effects of subanesthetic serial ketamine infusions in treatment resistant depression (Journal of Affective Disorders)

Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity on Youtube or Apple (Huberman Lab Podcast)

5 Minute Pearls: Ketamine for Treatment Resistant Depression and Suicidal Ideation (Psychiatrist.com)

Ketamine can be transformative for people with suicidal thoughts — if they can access it (STAT)

The efficacy of oral ketamine in severely depressed patients at high risk of suicide (Asian Journal of Psychiatry)

Clinical outcomes in the biomarkers of ketamine (Bio-K) study of open-label IV ketamine for refractory depression (Journal of Affective Disorders)

2-Minute Neuroscience: Ketamine (Neuroscientifically Challenged) 

Ketamine: A Paradigm Shift for Depression Research and Treatment (Neuron)

Ketamine Assisted Psychotherapy (KAP): Patient Demographics, Clinical Data and Outcomes in Three Large Practices Administering Ketamine with Psychotherapy (Journal of Psychoactive Drugs)

Ketamine and Personal Growth: The Transformative Power of Ketamine: Psychedelic States and a Personal History of Transformation (International Journal of Transpersonal Studies)

Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (The British Journal of Psychiatry)

A transdiagnostic systematic review and meta-analysis of ketamine’s anxiolytic effects (Journal of Psychopharmacology)

Intravenous ketamine for benzodiazepine deprescription and withdrawal management in treatment-resistant depression: a preliminary report (Neuropsychopharmacology)

Ketamine and Pain: Ketamine produces effective and long-term pain relief in patients with Complex Regional Pain Syndrome Type 1 (Pain)

Considering ketamine (for pain) (ACP Hospitalist, American College of Physicians) 

Ketamine at End of Life (ClinicalTrials.gov)

The potential of psychedelics for the treatment of Alzheimer's disease and related dementias (European Neuropsychopharmacology)

Dr. John Krystal — All Things Ketamine (The Tim Ferriss Show podcast)

Op-Comic: Ketamine had a reputation as a party drug. Could it help my depression? (Los Angeles Times)

About other psychedelics and healing:

The Potential of Psychedelics for End of Life and Palliative Care (Current Topics in Behavioral Neurosciences)

As Psychedelics Become More Mainstream, Here’s What You Need to Know (The Wall Street Journal)

Psychedelics and the Mind, University of California, Berkeley on edX (An excellent overview of the history and science of psychedelics)

The Trip Treatment (New Yorker on psychedelic therapy at end of life)

Psychedelics are Poised to Change How We Age and Die (Multidisciplinary Association for Psychedelic Studies)


Contact us: diane@ketaminejourneys.org